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Erythema induratum of Bazin

Erythema induratum of Bazin - PubMe

Erythema induratum of Bazin is a tuberculid that is strongly associated with tuberculosis. Clinically, erythema induratum of Bazin show recurrent tender subcutaneous nodules that occur mainly on the calves of women with tuberculin hypersensitivity Erythema induratum, also known as nodular vasculitis or Bazin disease, is categorized as a tuberculid skin eruption, which is a group of skin conditions associated with an underlying or silent..

Introduction: Erythema induratum of Bazin (EIB) is a rare tuberculid form characterized by hypersensitivity to Mycobacterium tuberculosis antigens. There are a few case series related to EIB in the literature. We evaluated the demographic, clinical, treatment, and follow-up characteristics of patients diagnosed with EIB

Slowing of the flow in the deep vessels can also encourage deposition of bacteria from the bloodstream, including tubercle bacilli, and in some patients, nodular vasculitis is a sign of tuberculosis, when it may be called erythema induratum or Bazin disease. What are the clinical features of nodular vasculitis Erythema induratum (EI) is an uncommon inflammatory disorder with alterations centered upon the subcutaneous fat tissue (panniculitis). The term EI was first proposed by Ernest Bazin in the mid-19 th century, who recognized the association of the distinctive clinical and histologic changes with tuberculosis (TB) [ 1,2 ] Erythema Induratum of Bazin (EIB) is a chronic nodular eruption that usually occurs on lower legs of young or middle aged women. Currently the term Nodular Vasculitis (NV) is often used as synonym, although historically considered as different entities

Erythema induratum

In 1861, Bazin gave the name erythema induratum to a nodular eruption that occurred on the lower legs of young women with tuberculosis. In 1945, Montgomery et al, while fully acknowledging the existence of tuberculosis-associated erythema induratum, coined the term nodular vasculitis to describe chronic inflammatory nodules of the legs that s.. Erythema induratum (of Bazin) is a tuberculosis-associated panniculitis which results in nodules on the backs of calves. It is different from erythema nodosum, which typically affects the shins and has a broad range of infectious and non-infectious precipitants. Lichen scrofulosorum is an eruption of multiple miniature follicular or. The term erythema induratum (EI) was coined by Bazin in 1855, who described deep violaceous nodules on the posterior lower legs of young women. EI presents clinically as recurrent crops of tender, violaceous nodules and plaques on the posterior lower legs. Lesions have also been reported on the feet, thighs, buttocks, and forearms Erythema induratum of Bazin is a disease that usually affects women, in whom erythematous subcutaneous nodules and plaques appear on the posterior part of the lower extremities, some of which ulcerate. In many countries, tuberculosis is still the main etiologic factor. We report a case of a 40-year-old woman wh Erythema induratum of Bazin (EIB) is a form of tuberculid resulting from hypersensitivity to tuberculosis antigen. EIB occurs most commonly in middle-aged women and is not typically seen in children. Here, we present a rare case of EIB, presenting as a chronic nodular panniculitis, in a 10-year-old Korean boy

From Wikipedia, the free encyclopedia Erythema induratum is a panniculitis on the calves. It occurs mainly in women, but it is very rare now. Historically, when it has occurred, it has often been concomitant with cutaneous tuberculosis, and it was formerly thought to be always a reaction to the TB bacteria Erythema induratum of Bazin (EIB) is a chronic, nodular eruption that usually occurs on the lower legs of otherwise heavyset women. EIB is a cutaneous manifestation of tuberculin hypersensitivity in association with Mycobacterium tuberculosis infection (e.g., tuberculoid) Erythema induratum of Bazin - nodular vasculitis - is a mostly tabular panniculitis with vasculitis, which affects almost exclusively adult females. Considered in the past to be a cutaneous manifestation of tuberculosis, this pathology is now thought more likely to be the result of a cell-mediated immune response to various exogenous or. Erythema induratum of Bazin (EIB) is a type of nodular vasculitis related to tuberculosis and . commonly presents with plaques and nodules on the lower extremities. Peripheral neuropathy may manifest as a result of a hypersensitivity reaction to tuberculosis antigens . causing tissue and nerve damage. Treatment of EIB and other cases of nodular. 1. J Am Acad Dermatol. 1990 Apr;22(4):612-6. Erythema induratum of Bazin as a type of tuberculid. Kuramoto Y(1), Aiba S, Tagami H. Author information: (1)Department of Dermatology, Tohoku University School of Medicine, Japan. We report three cases of patients with erythema induratum of Bazin who showed extreme tuberculin hypersensitivity reactions and a good therapeutic response to isoniazid

Erythema induratum of Bazin Victoria Sharon MD, Heidi Goodarzi MD, Cindy J Chambers MPH, Maxwell A Fung MD, April W Armstrong MD Dermatology Online Journal 16 (4): 1 University of California Davis, Sacramento, California Abstract. An 81-year-old woman with a history of renal cell carcinoma and years of slowly, progressively enlarging pulmonary nodules of uncertain etiology presented with. Erythema induratum was first identified in 1861, by Bazin, as a nodular eruption that occurred on the lower legs (posterior face) of young women with tuberculosis; in 1945, Montgomery et al described the histological hallmarks of this nodular panniculitis, while fully acknowledging its association with tuberculosis.15 Viable organisms in these. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (183K), or click on a page image below to browse page by page Erythema induratum of Bazin, a chronic form of nodular vasculitis, may be associated with chronic infections by Mycobacterium tuberculosis. However, the true origin of the disease is a subject of speculation and remains elusive. Two female patients (58 years old and 33 years old) with a minimum 10-year history of chronic tender ulcerating.

The tuberculous origin of erythema induratum (El), a chronic nodular eruption of the lower legs, has long remained circumstantial, since Mycobacteria cannot be cultured from lesional specimens. Erythema induratum is characterized by painful, erythematous, sometimes ulcerating nodules on the lower legs that, histopathologically, show a lobular panniculitis Erythema induratum of bazin (EIB) is a hypersensitivity reaction to Mycobacterium tuberculosis infection. The diagnosis can be difficult because tubercle.. Histopathological findings of erythema induratum of Bazin. A, Punch biopsy of the skin. B, There is vasculitis, focally granulomatous. C, Deep dermal and subcutaneous inflammation with a dense diffuse neutrophilic and granulomatous infiltrate. D, Widespread leukocytoclasia and necrosis without caseation

Erythema induratum of Bazin

  1. Erythema induratum of bazin: role of polymerase chain reaction in diagnosis. Sylvia S. Jacinto MD. Search for more papers by this author. Kristine B. Nograles MD. Search for more papers by this author. Sylvia S. Jacinto MD. Search for more papers by this author. Kristine B. Nograles MD
  2. Erythema induratum of Bazin (EIB) is a form of tuberculid resulting from hypersensitivity to tuberculosis antigen. EIB occurs most commonly in middle‐aged women and is not typically seen in children. Here, we present a rare case of EIB, presenting as a chronic nodular panniculitis, in a 10‐year‐old Korean boy
  3. Erythema induratum. Erythema induratum (Bazin disease) is the most commonly recognised form of tuberculid. It typically presents on the backs of the legs of young to middle-aged women as tender or painful indolent blue-red nodules and plaques which may ulcerate and scar. Erythema induratum of the lower limb
  4. Eur J Dermatol 2017; 27:410. Misago N, Narisawa Y. Erythema induratum (nodular vasculitis) associated with Crohn's disease: a rare type of metastatic Crohn's disease. Am J Dermatopathol 2012; 34:325. Pozdnyakova O, Garg A, Mahalingam M. Nodular vasculitis - a novel cutaneous manifestation of autoimmune colitis. J Cutan Pathol 2008; 35:315
  5. Erythema induratum of Bazin in a child: evidence for a cell-mediated hyper-response to Mycobacterium tuberculosis. Lighter J , Tse DB , Li Y , Borkowsky W Pediatr Infect Dis J , 28(4):326-328, 01 Apr 200
Erythema induratum of Bazin and Ponçet's arthropathy as

Erythema induratum is a panniculitis on the calves. It occurs mainly in women, but it is very rare defined pathogen. The medical eponym Bazin disease was historically synonymous, but it applies only to the tuberculous form and is dated. Erythema induratum (also referred to as erythema induratum of Bazin (EIB) or nodular vasculitis) is a chronic. Department of Dermatology, The University of São Paulo Medical School, São Paulo, Brazil. Search for more papers by this autho

DISCUSSION. Erythema induratum is synonymous with nodular vasculitis. When of tuberculous etiology, it has been called Bazin's disease or erythema induratum of Bazin; in nontuberculous cases, it is referred to as erythema induratum of Whitfield (Whitfield, 1901).The disease was first described by Bazin in 1861 as subcutaneous, indurated, erythematous nodules on the posterior lower legs of. Akiko Sekiguchi, Sei‐ichiro Motegi, Osamu Ishikawa, Erythema induratum of Bazin associated with bacillus Calmette-Guérin vaccination: Implication of M1 macrophage infiltration and monocyte chemotactic protein‐1 expression, The Journal of Dermatology, 10.1111/1346-8138.13148, 43, 1, (111-113), (2015) Erythema induratum of Bazin (EIB) is a tuberculid form of lobular panniculitis often occurring on the arms or legs with a clinical appearance similar to erythema nodosum but distinguished by characteristic nodular vasculitis on pathology [8, 9] Erythema induratum of Bazin is considered as a reactive skin disorder mainly associated with tuberculosis, typically presenting as subcutaneous nodules or indurated plaques with occasional ulcers on the calves in middle-aged women. With respect to clinical manifestations, this case was peculiar in that affected sites were more peripheral than.

Erythema induratum of Bazin is a chronic, nodular eruption that usually occurs on the lower legs of young women. It has been regarded as a manifestation of tuberculin hypersensitivity, a type of tuberculid occurring on the legs, whereas nodular vasculitis represents the nontuberculous counterpart. Bazin type was first discussed by Audry (1898), and later by Galloway (1899). However, Whitfield's (1901) name is par ticularly associated with a form of erythema induratum that is not tuberculous. Montgomery et al. (1944) stated that the following nodular vascular disorders of the legs have many features in common: nodular vasculitis, erythema. Bazin in was the first to describe erythema induratum as a benign induartum scrofulid; however, it was not until after the discovery of the Mycobacterium tuberculid in eriema the term scrofulid became commonly associated with TB

Erythema Induratum (Erythema induratum of Bazin, Nodular

Erythema induratum (EI), first described by Bazin [1], is characterized by chronic, recurrent, tender, indurated, and sometimes ulcerated subcutaneous nodules occurring mainly on the lower legs of women with moderate or high hypersensitivity to Mycobacte-rium tuberculosis. Histologically, EI is characterized by CONCLUSION:Erythema induratum of Bazin has distinct clinical, histopathologic, and immunohistochemical features. Erythema induratum of Bazin should be considered as a separate entity of nodular vasculitis caused by latent foci of tuberculous infection. Read Article at publisher's sit It occurs mainly in women, but it is very rare defined pathogen. The medical eponym Bazin disease was historically synonymous, but it applies only to the tuberculous form and is dated. Erythema induratum (also referred to as erythema induratum of Bazin (EIB) or nodular vasculitis) is a chronic nodular skin disease that is thought to represent a Erythema induratum of Bazin in a patient with endometrial tuberculosis. Biopsy sample was obtained and pathology showed septal and lobular hypodermitis with compromise of adipose lobules and lymphohistiocytic infiltrate that suggested the formation of granuloma, which was considered Bazin's Indurated Erythema

Bazin in was the first to describe erythema induratum as a benign erythematous scrofulid; however, it was not until after the discovery of the Mycobacterium tuberculid in that the term scrofulid became commonly associated with TB Erythema induratum represents a chronic skin disease most often caused by Mycobacterium tuberculosis, consisting of chronic inflammatory nodules commonly located on the lower limbs of the patient. Similarities exist between this condition and nodular vasculitis, but at this time the two are considered separate entities. Erythema Induratum (Bazins Disease): Read more about Symptoms. Erythema induratum of Bazin (EIB), also known as Bazin disease, tuberculosum, tuberculosis cutis indurativa and nodose tuberculid, is a chronic, nodular eruption that usually occurs on the lower legs of young women. It has been correlated wit Erythema induratum Bazin im Rahmen einer Tuberkulose gesehen. Rein histomorphologisch bestanden bei dichter Durchsetzung der Gefäßwand eines arteriellen Gefäßes an der Korium-Subkutis-Grenze Merkmalsüberschneidungen mit der Panarteritis nodosa. Diesbezügliche Zusatzuntersuchungen auf P-ANCA und C-ANCA im Serum der Patientin waren jedoch.

Erythema Induratum of Bazin - ScienceDirec

BACKGROUND: Erythema induratum of Bazin is a mostly lobular panniculitis. There is considerable controversy in the literature about whether or not vasculitis is a histopathologic requirement to establish the diagnosis of erythema induratum of Bazin. Even accepting vasculitis as a histopathologic. A 55‐year‐old man presented with recurrent multiple ulcerative nodules and plaques of 1‐year duration over the lower extremities. They were recalcitrant to topical (hydrocortisone cream) and systemic (pentoxyfylline, cefotiam) drugs. Skin surface examination of the affected areas showed the skin to be studded with violaceous nodules and/or plaques. A few of these had draining ulcers. The. Erythema induratum of bazin: role of polymerase chain reaction in diagnosis. Int J Dermatol. 2003 May. 42(5):380-1. . Chen YH, Yan JJ, Chao SC, Lee JY. Erythema induratum: a clinicopathologic and. Erythema induratum of Bazin in an infant after Bacille Calmette‐Guerin vaccination Erythema induratum of Bazin in an infant after Bacille Calmette‐Guerin vaccination INOUE, Tomoko; FUKUMOTO, Takaya; ANSAI, Shinichi; KIMURA, Tetsunori 2006-04-01 00:00:00 INTRODUCTION Erythema induratum of Bazin (EIB) is a tuberculid characterized by tender subcutaneous nodules that may be chronic, recurrent. Erythema induratum of Bazin EIBalso known as Bazin disease, tuberculosum, tuberculosis cutis indurativa and nodose tuberculid, is a chronic, nodular eruption that usually occurs on the lower legs of eritemz women

Pathology Outlines - Tuberculosis

The terms erythema induratum of Bazin and nodular vasculitis are sometimes used interchangeably, although others reserve the diagnosis of erythema induratum for cases associated with tuberculosis and nodular vasculitis for the remainder. Clinically, erythema induratum usually occurs in young or middle-aged women as firm violaceous nodules and. Erythema induratum of bazin is a hypersensitivity re-action to the tubercle bacillus. Tuberculin skin tests are strongly positive in most cases. Mycobacteriumtuberculosis DNA is often detected by PCR from lesions (10). However, a negative PCR does not rule out the diagnosis (1) Erythema Induratum of Bazin (EIB) is a tuberculid, a condition occurring 'on the legs of female and in young and plump well nourished women. It is characterized by recurrent nodular and ulcerative lesions. Lesions are usually localized to the lower legs especially calf area, but can affec erythema induratum of Bazin. Am J Dermatopathol 1997;19:323-33. 4. Vieites B, Suarez J, Penaranda M, et al. Recovery of Mycobacterium tuberculosis DNA in biopsies of erythema induratum — results in a series of patients using an improved polymerase chain reaction technique. Br J Dermatol 2005;152:1360-98. Figure 1. A erythema induratum and described its clinical and histopathologic features as different from those of erythema induratum of Bazin. Since then, most textbooks of dermatology described erythema indu-ratum of Bazin, erythema induratum of Whitfield, and nodular vasculitis as 3 different entities.7 Still, some current authors have proposed keeping th

The histopathologic spectrum of erythema induratum of Bazi

INTRODUCTION. Erythema induratum of Bazin (EIB) is a chronic nodular eruption that usually occurs on the legs of teenage and middle-aged women 5,15,20.It was first described by Bazin in 1861, and French dermatologists linked this condition to tuberculosis in 1900 5. The Mycobacterium tuberculosis has been hardly detected in the cutaneous lesions, so that this association has been refuted for a. Chen YH, Yan JJ, Chao SC, Lee JY. Erythema induratum: a clinico-pathologic and polymerase chain reaction study. J Formos Med Assoc 2001; 100: 244-9. CAS PubMed Google Scholar 7. Seckin D, Hizel N, Demirhan B, Tuncay C. The diagnostic value of polymerase chain reaction in erythema induratum of Bazin We report on a 6-year-old boy with tender subcutaneous lesions on his legs. A tuberculin skin test resulted in 2.5 cm of induration and an interferon-γ releasing assay was also markedly positive. A diagnosis of erythema induratum of Bazin was confirmed on skin biopsy. The patient was successfully treated with multi-drug antituberculosis therapy

Erythema Induratum (Nodular Vasculitis): Background

Two cases of erythema induratum of Bazin - a rare cutaneous manifestation of tuberculosis Sebastian von Huth, Anne Lindebo Øvrehus, Kim Hein Lindahl, Isik Somuncu Johansen; Affiliations Sebastian von Huth Department of Infectious Diseases, Odense University Hospital, Denmark. To the Editor: We have read the interesting paper by Schneider and Jordaan on the histopathology of 20 cases of erythema induratum of Bazin ; this article was a continuation of another one by Schneider et al. on the detection of Mycobacterium tuberculosis DNA in the same lesions of the same cases which was also published in The American Journal of Dermatopathology B azin1 first described erythema induratum (EI) in 1861 to illustrate chronic, painful, violaceous, indurated and occasionally ulcerative nodules that occurred predominantly on the lower limbs of patients (mainly women) with tuberculin hypersensitivity. Its appearance can easily be confused with erythema nodosum, polyarteritis nodosa or perniosis. The diagnosis of EI could easily have been. Mascaro JM, Basalga E. Erythema induratum of Bazin. Dermatol Clin. 2008;28:439-445.; Lighter J, Tse DB, Li Y, et al. Erythema induratum of Bazin in a child: evidence for a cell-mediated hyper-response to Mycobacterium tuberculosis. Pediatr Infect Dis J. 2009;28:326-328.; Inoue T, Fukumoto T, Ansai S, et al. Erythema induratum of Bazin in an infant after bacilli Calmette-Guerin vaccination

drMedicine by Sfakianakis G

Erythema Induratum (EI), a type of lobular panniculitis, is a benign skin condition that occurs on the calves. The condition is more often observed in young female adults. It is generally associated with tuberculosis (TB) of the skin. When Erythema Induratum is present in cutaneous tuberculosis, it is known as Erythema Induratum of Bazin (EIB Erythema induratum of Bazin (EIB) is considered a tuberculide reaction and consists of recurrent painful nodules predominantly on the calves. Clinically it has common features with diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum. Poncet's disease is a reactive arthritis that may accompany tuberculosis. We report a case of a young woman in which the. Erythema induratum of Bazin is a tuberculid that is strongly associated with tuberculosis. Clinically, erythema induratum of Bazin shows recurrent tender subcutaneous nodules that occur mainly on the calves of women with tuberculin hypersensitivity